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2010

Comprehensive Investigation of Marine Actinobacteria Associated with the Sponge Halichondria panicea

Schneemann, I., Nagel, K., Kajahn, I., Labes, A., Wiese, J., & Imhoff, J. F. (2010). Comprehensive Investigation of Marine Actinobacteria Associated with the Sponge Halichondria panicea. Applied and Environmental Microbiology, 76, 3702–3714. Abgerufen von http://oceanrep.geomar.de/8488/

Abstract

Representatives of Actinobacteria were isolated from the marine sponge Halichondria panicea collected from the Baltic Sea (Germany). For the first time, a comprehensive investigation was performed with regard to phylogenetic strain identification, secondary metabolite profiling, bioactivity determination, and genetic exploration of biosynthetic genes, especially concerning the relationships of the abundance of biosynthesis gene fragments to the number and diversity of produced secondary metabolites. All strains were phylogenetically identified by 16S rRNA gene sequence analyses and were found to belong to the genera Actinoalloteichus, Micrococcus, Micromonospora, Nocardiopsis, and Streptomyces. Secondary metabolite profiles of 46 actinobacterial strains were evaluated, 122 different substances were identified, and 88 so far unidentified compounds were detected. The extracts from most of the cultures showed biological activities. In addition, the presence of biosynthesis genes encoding polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) in 30 strains was established. It was shown that strains in which either PKS or NRPS genes were identified produced a significantly higher number of metabolites and exhibited a larger number of unidentified, possibly new metabolites than other strains. Therefore, the presence of PKS and NRPS genes is a good indicator for the selection of strains to isolate new natural products.
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2010

Journal Article

Imke Schneemann

Kerstin Nagel

Inga Kajahn

Antje Labes

Jutta Wiese

Johannes Imhoff

Microbiology

Biology

BIOSYNTHESIS GENE-CLUSTER

COMPLETE GENOME SEQUENCE

STREPTOMYCES SP

BIOLOGICAL PROPERTIES

POLYKETIDE SYNTHASE

NATURAL-PRODUCTS

PSEUDOCERATINA-CLAVATA

ANTIMYCIN ANTIBIOTICS

STRUCTURE ELUCIDATION

CHONDRILLA-NUCULA
Prioritizing countermeasures through the countermeasure method for software security (CM-Sec)

Baca, D., & Petersen, K. (2010). Prioritizing countermeasures through the countermeasure method for software security (CM-Sec). In International Conference on Product Focused Software Process Improvement (S. 176–190).
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Petersen, Kai

Abteilung/Einrichtung

FLAIR - Flensburg Artificial Intelligence Research
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2010

Conference Paper

Dejan Baca

Kai Petersen
Simulation-based Evaluation of Tactical Supply Chain Design Scenarios for New Product Introduction

Schilling, R., Brandenburg, M., & Kuhn, H. (2010). Simulation-based Evaluation of Tactical Supply Chain Design Scenarios for New Product Introduction. Porto, Portugal. Abgerufen von http://edoc.ku-eichstaett.de/5102/

Abstract

Based on a case study from the Fast Moving Consumer Goods (FMCG) industry, the paper analyzes and illustrates the simulation-based evaluation of tactical supply chain design (TSCD) scenarios for new product introduction (NPI). The task of TSCD for NPI is to establish product-specific supply chains that cost-efficiently ensure on time and in full availability of new high quality products over the whole product life cycles (PLC). The problem complexity is driven by cross-regional network aspects and inter-disciplinary factors as well as by dynamics and uncertainty in short PLCs. Keywords: Fast Moving Consumer Goods, New Product Introduction, Tactical Supply Chain Design
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Brandenburg, Marcus
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2010

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Robert Schilling

Marcus Brandenburg

Heinrich Kuhn

2009

Wassergefüllte U-Pumpenmotoren in PM-Synchrontechnik

Löhlein, B., & Huth, G. (2009). Wassergefüllte U-Pumpenmotoren in PM-Synchrontechnik. In ETG-Fachbericht 119 zum Internationalen ETG-Kongress. VDE Verlag GmbH. (Original work published 2025)
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2009

Conference Paper

Bernd Löhlein

Gerhard Huth

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Autonomous Optimization of UWB Link Access

Pérez-Guirao, M. D., Lübben, R., & Kaiser, T. (2009). Autonomous Optimization of UWB Link Access. Frequenz, 63, 196–199. http://doi.org/10.1515/FREQ.2009.63.9-10.196 (Original work published 2025)
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Lübben, Ralf

Fachbereich

Fachbereich 4: Wirtschaft
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2009

Journal Article

M. Pérez-Guirao

Ralf Lübben

T. Kaiser
Development of a wind turbine LiDAR simulator

Schlipf, D., Trujillo, J. J., Basterra, V., & Kühn, M. (2009). Development of a wind turbine LiDAR simulator. In European Wind Energy Conference. Marseille, France. http://doi.org/10.18419/opus-3914 (Original work published 2025)
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Schlipf, David
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2009

Conference Paper

David Schlipf

Juan Trujillo

Valeria Basterra

Martin Kühn
Fast Rerouting for IP Multicast in Managed IPTV Networks

Lübben, R., Li, G., Wang, D., Doverspike, R., & Fu, X. (2009). Fast Rerouting for IP Multicast in Managed IPTV Networks. In IEEE IWQoS. http://doi.org/10.1109/IWQoS.2009.5201406 (Original work published 2025)
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Lübben, Ralf

Fachbereich

Fachbereich 4: Wirtschaft
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2009

Conference Paper

Ralf Lübben

G. Li

D. Wang

R. Doverspike

X. Fu
Control of the Pareto Optimality of Systems with Unknown Disturbances

Geisler, J., & Trächtler, A. (2009). Control of the Pareto Optimality of Systems with Unknown Disturbances. In Proceedings of the 7th International Conference on Control and Automation (ICCA09). Christchurch, New Zealand. http://doi.org/10.1109/ICCA.2009.5410424 (Original work published Dezember 2009)

Abstract

In this paper we treat the classical linear-quadratic regulator (LQR) design as an online multi-objective optimization problem where the compromise between the multiple objective functions is not resolved until run-time. For this purpose the unknown Pareto front is locally approximated by the gradient of the objective functions. Then, using a superordinated control loop, the Pareto optimality is adjusted to an arbitrary point on the Pareto front. This makes it possible to react to unknown or slowly varying stochastic disturbances or changing optimality requirements. Also, the control engineer is no longer concerned with determining suitable weighting matrices as in the classical LQR design. Instead, a compromise between the contradicting objectives is sought by means of physically or economically interpretable rules. It is shown that the gradients of the objective functions that depend on the currently effective disturbances can be computed from the system state through fictitious outputs. This allows a very efficient implementation of the proposed regulator scheme without knowledge of the disturbances.
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Geisler, Jens
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2009

Conference Paper

Jens Geisler

Ansgar Trächtler
Verlässlichkeit im aktiven selbstoptimierenden Spurführungsmodul eines schienengebundenen Fahrzeugs

Sondermann-Wölke, C., Geisler, J., Hirsch, M., & Hemsel, T. (2009). Verlässlichkeit im aktiven selbstoptimierenden Spurführungsmodul eines schienengebundenen Fahrzeugs. In J. Gausemeier, F. J. Rammig, W. Schäfer, & A. Trächtler (Hrsg.), Entwurf mechatronischer Systeme (Bd. 250). Paderborn: HNI-Verlagsschriftenreihe. (Original work published April 2009)
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Geisler, Jens
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2009

Book Chapter

Christoph Sondermann-Wölke

Jens Geisler

M. Hirsch

T. Hemsel

J. Gausemeier

F. Rammig

W. Schäfer

A. Trächtler
Datenhoheit dem Souverän - die Genossenschaft als Betreiber der eGA

Friesdorf, W., & Podtschaske, B. (2009). Datenhoheit dem Souverän - die Genossenschaft als Betreiber der eGA. In O. Lorenz (Hrsg.), Jahrbuch Gesundheitswirtschaft 2009: Prozessoptimierung,eHealth und Vernetzung (S. 92). Berlin: Wegweiser GmbH.
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Podtschaske, Beatrice

Profilbereich

Gesundheit und Life Sciences

Fachbereich

Fachbereich 4: Wirtschaft
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2009

Book Chapter

Wolfgang Friesdorf

Beatrice Podtschaske

Oliver Lorenz

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