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2025

Comprehensive Dataset of Coarse Tumor Annotations for The Cancer Genome Atlas Breast Invasive Carcinoma

Banerjee, S. ", Bertram, C. A., Ammeling, J. ., Weiss, V. ., Conrad, T. ., Klopfleisch, R. ., … Aubreville, M. . (2025). Comprehensive Dataset of Coarse Tumor Annotations for The Cancer Genome Atlas Breast Invasive Carcinoma. In Bildverarbeitung für die Medizin 2025 (S. 260–265). Wiesbaden: Springer Fachmedien Wiesbaden. http://doi.org/10.1007/978-3-658-47422-5_56

Abstract

Automated tumor segmentation of histologic images is crucial for the development of computer-assisted diagnostic workflows aiming at accurate prognostication. We present a dataset of coarse annotations of over 1,000 highresolution breast tumor images from The cancer genome atlas breast invasive carcinoma (TCGA-BRCA) repository, each annotated with binary segmentation masks that delineate coarse tumor areas. Additionally, a subset of 20 images includes fine-grained annotations, providing precise delineation of tumor boundaries beyond the broader outlines used in coarse annotations. Initial evaluations using U-Net and DeepLabv3 models show promising segmentation performance. On a held-out, coarsely annotated test set, U-Net achieved an average intersection over union (IoU) score of 0.795, while DeepLabv3 scored 0.783. On the finely annotated subset of this test set, U-Net reached an average IoU of 0.746, with DeepLabv3 slightly outperforming at 0.765. The public availability of this dataset aims to support research in automated tumor analysis, advancing diagnostic workflows and thereby ultimately improving breast cancer management.
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Aubreville, Marc

Forschungsprojekt

Robust and Accurate Multi-Tumor, Multi-Species, Multi-Laboratory and Multi-Scanner Mitosis Detection with Large-Scale Datasets and Artificial Intelligence

Abteilung/Einrichtung

CIVU – Center for Interaction, Visualization and Usability

FLAIR - Flensburg Artificial Intelligence Research

Profilbereich

Gesundheit und Life Sciences

Forschungsfeld

Data Science und Künstliche Intelligenz

Fachbereich

Fachbereich 3: Information und Kommunikation
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2025

Conference Paper

Sweta Banerjee

Christof Bertram

Jonas Ammeling

Viktoria Weiss

Thomas Conrad

Robert Klopfleisch

Christopher Kaltenecker

Katharina Breininger

Marc Aubreville
Investigation of Class Separability within Object Detection Models in Histopathology

Ammeling, J. ., Ganz, J. ., Wilm, F. ., Breininger, K. ., & Aubreville, M. . (2025). Investigation of Class Separability within Object Detection Models in Histopathology. IEEE Transactions on Medical Imaging, 1–1. http://doi.org/10.1109/TMI.2025.3560134
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Aubreville, Marc

Forschungsprojekt

Robust and Accurate Multi-Tumor, Multi-Species, Multi-Laboratory and Multi-Scanner Mitosis Detection with Large-Scale Datasets and Artificial Intelligence

Abteilung/Einrichtung

FLAIR - Flensburg Artificial Intelligence Research

Profilbereich

Informatik und Gestaltung

Forschungsfeld

Data Science und Künstliche Intelligenz

Fachbereich

Fachbereich 3: Information und Kommunikation
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2025

Journal Article

Jonas Ammeling

Jonathan Ganz

Frauke Wilm

Katharina Breininger

Marc Aubreville

Feature extraction

Object detection

Measurement

Adaptation models

histopathology

Training

Complexity theory

YOLO

Location awareness

Data mining

object detection

latent space discrimination
Reduction of torque ripple in electric drives with concentrated windings through unconventional stator slot numbers

Königs, M. ., & Löhlein, B. . (2025). Reduction of torque ripple in electric drives with concentrated windings through unconventional stator slot numbers. e+i Elektrotechnik Und Informationstechnik.
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2025

Journal Article

Mike Königs

Bernd Löhlein
Histologic Dataset of Normal and Atypical Mitotic Figures on Human Breast Cancer (AMi-Br)

Bertram, C. A. ", Weiss, V. ., Donovan, T. A., Banerjee, S. ., Conrad, T. ., Ammeling, J. ., … Aubreville, M. . (2025). Histologic Dataset of Normal and Atypical Mitotic Figures on Human Breast Cancer (AMi-Br). In "Bildverarbeitung für die Medizin 2025" (S. 113–118). "Wiesbaden": "Springer Fachmedien Wiesbaden".

Abstract

"Assessment of the density of mitotic figures (MFs) in histologic tumor sections is an important prognostic marker for many tumor types, including breast cancer. Recently, it has been reported in multiple works that the quantity of MFs with an atypical morphology (atypical MFs, AMFs) might be an independent prognostic criterion for breast cancer. AMFs are an indicator of mutations in the genes regulating the cell cycle and can lead to aberrant chromosome constitution (aneuploidy) of the tumor cells. To facilitate further research on this topic using pattern recognition, we present the first ever publicly available dataset of atypical and normal MFs (AMi-Br). For this, we utilized two of the most popular MF datasets (MIDOG 2021 and TUPAC) and subclassified all MFs using a three expert majority vote. Our final dataset consists of 3,720 MFs, split into 832 AMFs (22.4\%) and 2,888 normal MFs (77.6\%) across all 223 tumor cases in the combined set. We provide baseline classification experiments to investigate the consistency of the dataset, using a Monte Carlo cross-validation and different strategies to combat class imbalance.We found an averaged balanced accuracy of up to 0.806 when using a patch-level data set split, and up to 0.713 when using a patient-level split."
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Aubreville, Marc

Forschungsprojekt

Robust and Accurate Multi-Tumor, Multi-Species, Multi-Laboratory and Multi-Scanner Mitosis Detection with Large-Scale Datasets and Artificial Intelligence

Abteilung/Einrichtung

FLAIR - Flensburg Artificial Intelligence Research

CIVU – Center for Interaction, Visualization and Usability

Profilbereich

Gesundheit und Life Sciences

Forschungsfeld

Digitale Transformation

Human-Computer-Interaction

Data Science und Künstliche Intelligenz

Fachbereich

Fachbereich 3: Information und Kommunikation
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2025

Conference Paper

Christof Bertram

Viktoria Weiss

Taryn Donovan

Sweta Banerjee

Thomas Conrad

Jonas Ammeling

Robert Klopfleisch

Christopher Kaltenecker

Marc Aubreville

2024

Prediction of tumor board procedural recommendations using large language models

Aubreville, M. ., Ganz, J. ., Ammeling, J. ., Rosbach, E. ., Gehrke, T. ., Scherzad, A. ., … Goncalves, M. . (2024). Prediction of tumor board procedural recommendations using large language models. European Archives of Oto-Rhino-Laryngology. http://doi.org/10.1007/s00405-024-08947-9 (Original work published 2025)

Abstract

Multidisciplinary tumor boards are meetings where a team of medical specialists, including medical oncologists, radiation oncologists, radiologists, surgeons, and pathologists, collaborate to determine the best treatment plan for cancer patients. While decision-making in this context is logistically and cost-intensive, it has a significant positive effect on overall cancer survival.
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Aubreville, Marc

Abteilung/Einrichtung

FLAIR - Flensburg Artificial Intelligence Research

Profilbereich

Informatik und Gestaltung

Forschungsfeld

Digitalisierung im Gesundheitswesen

Data Science und Künstliche Intelligenz

Fachbereich

Fachbereich 3: Information und Kommunikation
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2024

Journal Article

Marc Aubreville

Jonathan Ganz

Jonas Ammeling

Emely Rosbach

Thomas Gehrke

Agmal Scherzad

Stephan Hackenberg

Miguel Goncalves
Re-identification from histopathology images

Ganz, J. ., Ammeling, J. ., Jabari, S. ., Breininger, K. ., & Aubreville, M. . (2024). Re-identification from histopathology images. Medical Image Analysis, 103335. http://doi.org/10.1016/j.media.2024.103335 (Original work published 2025)
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Aubreville, Marc

Abteilung/Einrichtung

FLAIR - Flensburg Artificial Intelligence Research

Forschungsfeld

Digitalisierung im Gesundheitswesen

Data Science und Künstliche Intelligenz

Fachbereich

Fachbereich 3: Information und Kommunikation
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2024

Journal Article

Jonathan Ganz

Jonas Ammeling

Samir Jabari

Katharina Breininger

Marc Aubreville
Study on the impact of wind models and data processing on lidar-assisted control performance

Fu, W. ., Schlipf, D. ., Raach, S. ., White, S. ., Pitter, M. ., & Slinger, C. . (2024). Study on the impact of wind models and data processing on lidar-assisted control performance. http://doi.org/10.5281/zenodo.12666568 (Original work published 2025)
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Schlipf, David
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2024

Miscellaneous

Wei Fu

David Schlipf

Steffen Raach

Steven White

Mark Pitter

Chris Slinger
Contribution of wind energy education to resilience in the face of the climate crisis

Schlipf, D. ., Soto, G. Q., Rodriguez, H. Z., & Brovia, S. P. (2024). Contribution of wind energy education to resilience in the face of the climate crisis. http://doi.org/10.5281/zenodo.13270425 (Original work published 2025)
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Schlipf, David
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2024

Miscellaneous

David Schlipf

Grace Soto

Habib Rodriguez

Santiago Brovia
IEA Wind Task 52 LAC Summer Games 2024

Schlipf, D. ., Guo, F. ., Liang, Z. ., Pitter, M. ., Lopez-Queija, J. ., Rinker, J. ., … Weich, S. . (2024). IEA Wind Task 52 LAC Summer Games 2024. http://doi.org/10.5281/zenodo.13235189 (Original work published 2025)
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Schlipf, David
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2024

Miscellaneous

David Schlipf

Feng Guo

Zhi Liang

Mark Pitter

Javier Lopez-Queija

Jenni Rinker

Aravind Venkatachalapathy

Simon Weich
Navigating the complexities of a changing world - Interdisciplinary Electives at Flensburg University of Applied Sciences

van der Sluis, H. ., & John, P. . (2024). Navigating the complexities of a changing world - Interdisciplinary Electives at Flensburg University of Applied Sciences. Educational Developments, 25.4, 4. Abgerufen von https://www.seda.ac.uk/seda-publishing/educational-developments/educational-developments-issue-25-4-2024/ (Original work published Dezember 2024)

Abstract

In a competitive Higher Education (HE) landscape, universities face the challenge of developing an organisational culture that supports the needs of its staff and students. The traditional staff development approach has been the attainment of skills through teaching and the completion of certificates of learning. This article challenges that practice and seeks to make the case for a renewed focus on the importance of learning through individual and group coaching practice to be ingrained into universities, shifting from a view of staff development purely as the acquisition of skills through training and teaching and moving towards
engaged learning.
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John, Peter

Abteilung/Einrichtung

Dekanat FB3

Lern- und Sprachenzentrum (LSZ)

Forschungsfeld

Fachkräfte und Vernetzung

Fachbereich

Fachbereich 3: Information und Kommunikation
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2024

Journal Article

Hendrik van der Sluis

Peter John

Publikationen

2025

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2024

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