Publikationen

2013

• Integrated Therapy Safety Management System

  Podtschaske, B., Fuchs, D., & Friesdorf, W. (2013). Integrated Therapy Safety Management System. British Journal of Clinical Pharmacology, 76(Suppl 1), 5–13. http://doi.org/https://doi.org/10.1111/bcp.12155 (Original work published September 2013)

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  The aim is to demonstrate the benefit of the medico-ergonomic approach for the redesign of clinical work systems. Based on the six layer model, a concept for an ‘integrated therapy safety management’ is drafted. This concept could serve as a basis to improve resilience. Methods The concept is developed through a concept-based approach. The state of the art of safety and complexity research in human factors and ergonomics forms the basis. The findings are synthesized to a concept for ‘integrated therapy safety management’. The concept is applied by way of example for the ‘medication process’ to demonstrate its practical implementation. Results The ‘integrated therapy safety management’ is drafted in accordance with the six layer model. This model supports a detailed description of specific work tasks, the corresponding responsibilities and related workflows at different layers by using the concept of ‘bridge managers’. ‘Bridge managers’ anticipate potential errors and monitor the controlled system continuously. If disruptions or disturbances occur, they respond with corrective actions which ensure that no harm results and they initiate preventive measures for future procedures. The concept demonstrates that in a complex work system, the human factor is the key element and final authority to cope with the residual complexity. The expertise of the ‘bridge managers’ and the recursive hierarchical structure results in highly adaptive clinical work systems and increases their resilience. Conclusions The medico-ergonomic approach is a highly promising way of coping with two complexities. It offers a systematic framework for comprehensive analyses of clinical work systems and promotes interdisciplinary collaboration.

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    • Podtschaske, Beatrice

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    • Gesundheit und Life Sciences

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    • Fachbereich 4: Wirtschaft

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  • Journal Article
  • • Beatrice Podtschaske
    • Daniela Fuchs
    • Wolfgang Friesdorf
  • • six layer model
    • complexity
    • drug therapy
    • medico-ergonomic
    • resilience
    • workflow

• Calcaripeptides A?C, Cyclodepsipeptides from a Calcarisporium Strain

  Silber, J., Ohlendorf, B., Labes, A., Näther, C., & Imhoff, J. F. (2013). Calcaripeptides A?C, Cyclodepsipeptides from a Calcarisporium Strain. Journal of Natural Products, 76, 1461–1467. Abgerufen von http://oceanrep.geomar.de/21997/ (Original work published Juli 2013)

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  The isolation and structure elucidation of the novel calcaripeptides A (1), B (2), and C (3) and studies on their biosynthetic origin are described. The calcaripeptides were identified from Calcarisporium sp. strain KF525, which was isolated from the German Wadden Sea. Compounds 1?3 are macrocyclic structures composed of a proline and a phenylalanine residue as well as a nonpeptidic substructure. Structure elucidation was achieved by applying one- and two-dimensional NMR spectroscopy supported by high-resolution mass spectrometry. X-ray crystallography was performed to determine the relative configuration of 1. The absolute configuration of 1 was assigned by HPLC of the amino acids after hydrolysis of the molecule and derivatization with chiral agents. Studies on the biosynthesis by feeding 13C-labeled substrates revealed that the nonpeptidic part of 1 originates from acetate and l-methionine. The involvement of a hybrid between a polyketide synthase and a nonribosomal peptide synthetase in the biosynthesis of the calcaripeptides is discussed.

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  • 2013
  • Journal Article
  • • Johanna Silber
    • Birgit Ohlendorf
    • Antje Labes
    • Christian Näther
    • Johannes Imhoff

• Konzeptstudie für Windenergieanlage mit Azimutlager am Turmfuß

  Faber, P. D.-I. T., Beye, T., & Rudolf, R. (2013). Konzeptstudie für Windenergieanlage mit Azimutlager am Turmfuß. Bauingenieur, (6), 6. (Original work published Juni 2013)

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    • Faber, Torsten

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  • 2013
  • Journal Article
  • • Prof. Dr.-Ing. Torsten Faber
    • T. Beye
    • R. Rudolf
  • • WETI

• Information density in bridge team communication and miscommunication—a quantitative approach to evaluate maritime communication

  John, P., Brooks, B., Wand, C., & Schriewer, U. (2013). Information density in bridge team communication and miscommunication—a quantitative approach to evaluate maritime communication. WMU Journal of Maritime Affairs, 12, 16. http://doi.org/https://doi.org/10.1007/s13437-013-0043-8 (Original work published März 2013)

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  The paper presents a method for measuring the information flow in bridge team communication based on an analysis of the voyage data recorder transcript of MV Cosco Busan alliding with a bridge pillar in San Francisco Bay in dense fog. The aim is to assess the efficiency of maritime communication by developing a specific index suitable for evaluating individual and team communication performance. The allision investigated in this paper leads to the conclusion that the information flow in bridge team communication can be measured quantitatively and that a correlation to external situational factors can be demonstrated.

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    • John, Peter

  • Fachbereich

    • Fachbereich 3: Information und Kommunikation

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  • 2013
  • Journal Article
  • • Peter John
    • Benjamin Brooks
    • Christoph Wand
    • Ulf Schriewer
  • • Maritime communication
    • Bridge team communication
    • Voyage data recorder
    • Quantitative linguistics

• Generalized class invariants with "Thetanullwerte"

  Uzunkol, O. (2013). Generalized class invariants with "Thetanullwerte". Turkish Journal of Mathematics, 37, 165–181. http://doi.org/10.3906/mat-1106-4

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    • Uzunkol, Osmanbey

  • Fachbereich

    • Fachbereich 3: Information und Kommunikation

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  • 2013
  • Journal Article
  • • Osmanbey Uzunkol

• A decision support framework for metrics selection in goal-based measurement programs: GQM-DSFMS

  Gencel, C., Petersen, K., Mughal, A. A., & Iqbal, M. I. (2013). A decision support framework for metrics selection in goal-based measurement programs: GQM-DSFMS. Journal of Systems and Software, 86, 3091–3108.

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    • Petersen, Kai

  • Abteilung/Einrichtung

    • FLAIR - Flensburg Artificial Intelligence Research

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  • 2013
  • Journal Article
  • • Cigdem Gencel
    • Kai Petersen
    • Aftab Mughal
    • Muhammad Iqbal

• Improving software security with static automated code analysis in an industry setting

  Baca, D., Carlsson, B., Petersen, K., & Lundberg, L. (2013). Improving software security with static automated code analysis in an industry setting. Software: Practice and Experience, 43, 259–279.

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    • Petersen, Kai

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    • FLAIR - Flensburg Artificial Intelligence Research

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  • 2013
  • Journal Article
  • • Dejan Baca
    • Bengt Carlsson
    • Kai Petersen
    • Lars Lundberg

• Algae as important environment for bacteria - phylogenetic relationships among species isolated from algae

  Goecke, F. R., Thiel, V., Wiese, J., Labes, A., & Imhoff, J. F. (2013). Algae as important environment for bacteria - phylogenetic relationships among species isolated from algae. Phycologia, 52, 14–24. Abgerufen von http://oceanrep.geomar.de/19593/

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  Bacteria are an inherent part of the biotic environment of algae. Recent investigations revealed that bacterial communities associated with algae were generally highly host specific. Several new bacterial species and genera were isolated from algae, which suggested that algae were an interesting environment for discovery of new bacterial taxa; however, the distribution of the different phylogenetic groups among those isolates remained unclear, and this information could help to explain specific associations. We conducted a phylogenetic study based on 16S rRNA gene sequences available in GenBank, including 101 validly described bacterial species that were isolated from eukaryotic macro- and micro-algae from marine and freshwater environments. These species were distributed among six bacterial phyla, including: Bacteroidetes (42 species), Proteobacteria (36 species), and Firmicutes, Actinobacteria, Verrucomicrobia and Planctomycetes (23 species). Bacterial species and strains that carried out similar metabolic functions were found to colonize similar algal taxa or algal groups. This assumption was supported by information available from bacterial species descriptions: (1) Most of the bacteria described from microalgae grouped into the Roseobacter clade (Alphaproteobacteria), which indicated that members of this group were well adapted for life in close association with phytoplankton; and (2) 32\% of the bacterial species, mainly isolates from macroalgae, were able to decompose macroalgal polysaccharides. Because algal-bacterial association are still under-studied in various algal groups, we expect a great number of new bacterial taxa to be discovered in the future.

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  • 2013
  • Journal Article
  • • Franz Goecke
    • Vera Thiel
    • Jutta Wiese
    • Antje Labes
    • Johannes Imhoff
  • • Enzyme
    • Macroalgae
    • Microbe-alga
    • Phytoplankton
    • DINOFLAGELLATE GYMNODINIUM-CATENATUM
    • MARINE ROSEOBACTER LINEAGE
    • DISSOLVED ORGANIC-MATTER
    • IN-SITU HYBRIDIZATION
    • EPIPHYTIC BACTERIAL
    • LAMINARIA-JAPONICA
    • GEN. NOV.
    • COMMUNITY COMPOSITION
    • ALEXANDRIUM SPP.
    • BROWN ALGA

• Einwirkungen auf das Bauwerk Offshore-Windenergieanlage

  Faber, P. D.-I. T., & Klinke, L. (2013). Einwirkungen auf das Bauwerk Offshore-Windenergieanlage. Bauingenieur, 5.

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    • Faber, Torsten

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  • 2013
  • Journal Article
  • • Prof. Dr.-Ing. Torsten Faber
    • L. Klinke
  • • WETI

• Analyzing an automotive testing process with evidence-based software engineering

  Kasoju, A., Petersen, K., & Mäntylä, M. , V. (2013). Analyzing an automotive testing process with evidence-based software engineering. Information and Software Technology, 55, 1237–1259.

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    • Petersen, Kai

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    • FLAIR - Flensburg Artificial Intelligence Research

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  • 2013
  • Journal Article
  • • Abhinaya Kasoju
    • Kai Petersen
    • Mika Mäntylä V