Publikationen

2013

• Einwirkungen auf das Bauwerk Offshore-Windenergieanlage

  Faber, P. D.-I. T. ., & Klinke, L. . (2013). Einwirkungen auf das Bauwerk Offshore-Windenergieanlage. Bauingenieur, 5.

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    • Faber, Torsten

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  • 2013
  • Journal Article
  • • Prof. Dr.-Ing. Torsten Faber
    • L. Klinke
  • • WETI

• Improving software security with static automated code analysis in an industry setting

  Baca, D. ., Carlsson, B. ., Petersen, K. ., & Lundberg, L. . (2013). Improving software security with static automated code analysis in an industry setting. Software: Practice and Experience, 43, 259–279.

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    • Petersen, Kai

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    • FLAIR - Flensburg Artificial Intelligence Research

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  • 2013
  • Journal Article
  • • Dejan Baca
    • Bengt Carlsson
    • Kai Petersen
    • Lars Lundberg

• Bio-mining the microbial treasures of the ocean: Early drug discovery and models for entering pharmaceutical pipelines

  Labes, A. . (2013). Bio-mining the microbial treasures of the ocean: Early drug discovery and models for entering pharmaceutical pipelines. In SUBMARINER. Abgerufen von http://oceanrep.geomar.de/23002/

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  • 2013
  • Conference Paper
  • • Antje Labes

• Water_130503

  Clemens, A. . (2013). Water_130503.

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  Gruppenausstellung BewegungsARTen,

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  • Personenseiten

    • Clemens, Angela

  • Profilbereich

    • Informatik und Gestaltung

  • Forschungsfeld

    • Kreativwirtschaft

  • Fachbereich

    • Fachbereich 3: Information und Kommunikation

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  • 2013
  • Artwork
  • • Angela Clemens

• Algae as important environment for bacteria - phylogenetic relationships among species isolated from algae

  Goecke, F. R., Thiel, V. ., Wiese, J. ., Labes, A. ., & Imhoff, J. F. (2013). Algae as important environment for bacteria - phylogenetic relationships among species isolated from algae. Phycologia, 52, 14–24. Abgerufen von http://oceanrep.geomar.de/19593/

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  Bacteria are an inherent part of the biotic environment of algae. Recent investigations revealed that bacterial communities associated with algae were generally highly host specific. Several new bacterial species and genera were isolated from algae, which suggested that algae were an interesting environment for discovery of new bacterial taxa; however, the distribution of the different phylogenetic groups among those isolates remained unclear, and this information could help to explain specific associations. We conducted a phylogenetic study based on 16S rRNA gene sequences available in GenBank, including 101 validly described bacterial species that were isolated from eukaryotic macro- and micro-algae from marine and freshwater environments. These species were distributed among six bacterial phyla, including: Bacteroidetes (42 species), Proteobacteria (36 species), and Firmicutes, Actinobacteria, Verrucomicrobia and Planctomycetes (23 species). Bacterial species and strains that carried out similar metabolic functions were found to colonize similar algal taxa or algal groups. This assumption was supported by information available from bacterial species descriptions: (1) Most of the bacteria described from microalgae grouped into the Roseobacter clade (Alphaproteobacteria), which indicated that members of this group were well adapted for life in close association with phytoplankton; and (2) 32\% of the bacterial species, mainly isolates from macroalgae, were able to decompose macroalgal polysaccharides. Because algal-bacterial association are still under-studied in various algal groups, we expect a great number of new bacterial taxa to be discovered in the future.

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  • 2013
  • Journal Article
  • • Franz Goecke
    • Vera Thiel
    • Jutta Wiese
    • Antje Labes
    • Johannes Imhoff
  • • Enzyme
    • Macroalgae
    • Microbe-alga
    • Phytoplankton
    • DINOFLAGELLATE GYMNODINIUM-CATENATUM
    • MARINE ROSEOBACTER LINEAGE
    • DISSOLVED ORGANIC-MATTER
    • IN-SITU HYBRIDIZATION
    • EPIPHYTIC BACTERIAL
    • LAMINARIA-JAPONICA
    • GEN. NOV.
    • COMMUNITY COMPOSITION
    • ALEXANDRIUM SPP.
    • BROWN ALGA

• Higher yields of cyclodepsipetides from Scopulariopsis brevicaulis by random mutagenesis

  Paun, L. ., Kramer, A. ., Hihlal, E. ., Labes, A. ., Imhoff, J. F., & Kempken, F. . (2013). Higher yields of cyclodepsipetides from Scopulariopsis brevicaulis by random mutagenesis. In 27. Fungal Genetics Conference. Abgerufen von http://oceanrep.geomar.de/22016/

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  The ascomycete Scopulariopsis brevicaulis, which was isolated from the marine sponge Tethya aurantium, produces two cyclodepsipeptides, scopularides A and B [1]. Both peptides exhibit activity against several tumor cell lines. Within the EU-project MARINE FUNGI (EU FP7, 265926) one of our aims is to enhance the production of these secondary metabolites. We are in the process to establish two ways of random mutagenesis by both UV radiation and transposon-mediated. To this end we created UV-mutants and a miniaturised screening method was developed. UV-radiation was performed at 312 nm and the survival rate was set to 1 \%. With this method a mutant library was established. To screen these mutants for higher secondary metabolites production, we developed a miniaturised screening method which includes decreased cultivation volume, fast extraction and an optimised LC-MS analysis format. Using the UV mutagenesis, we were able to identify several mutants with a higher scopularide production in comparison to the wild type. One of these mutants, which produces three times more biomass and more than double the amount of scopularide A, has been used for another round of mutation. Next generation sequencing is being employed to identify the molecular genetic basis of the observed mutations. In parallel we employ transposable elements to introduce mutants [2]. The impact of transposons on gene expression as well as their ability to cause major mutations within the genome or single genes makes them an interesting tool for random mutagenesis [3, 4, 5]. We employ the Vader transposon in its homologous host and found that Vader mostly integrates within or very close to genes. Thus it appears to be a useful tool for transposon-mediated mutagenesis in A. niger (6). At current we try to enhance its usability by modifying the Vader element.

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  • 2013
  • Conference Paper
  • • Linda Paun
    • Annemarie Kramer
    • ElKbir Hihlal
    • Antje Labes
    • Johannes Imhoff
    • Frank Kempken

• On rapid releases and software testing

  Mäntylä, M. . , V, Khomh, F. ., Adams, B. ., Engström, E. ., & Petersen, K. . (2013). On rapid releases and software testing. In 2013 IEEE International Conference on Software Maintenance (S. 20–29).

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    • Petersen, Kai

  • Abteilung/Einrichtung

    • FLAIR - Flensburg Artificial Intelligence Research

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  • 2013
  • Conference Paper
  • • Mika Mäntylä V
    • Foutse Khomh
    • Bram Adams
    • Emelie Engström
    • Kai Petersen

• Das Meer erforschen und Medizin finden

  Labes, A. . (2013). Das Meer erforschen und Medizin finden. In Zukunft Meer - Ein Abend über das Erforschen, die Nutzung und den Schutz der Meere. Abgerufen von http://oceanrep.geomar.de/23010/

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  • 2013
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  • • Antje Labes

• Quantitative Models for Value-Based Supply Chain Management

  Brandenburg, M. . (2013). Quantitative Models for Value-Based Supply Chain Management. Lecture Notes in Economics and Mathematical Systems (S. 219). Berlin, Heidelberg: Springer. http://doi.org/10.1007/978-3-642-31304-2

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  Supply chain management (SCM) strives for creating competitive advantage and value for customers by integrating business processes from end users through original suppliers. However, the question of how SCM influences the value of a firm is not fully answered. Various conceptual frameworks that explain the coherence of SCM and company value, comprehended as value-based SCM, are well accepted in scientific research, but quantitative approaches to value-based SCM are found rather seldom. The book contributes to this research gap by proposing quantitative models that allow for assessing influences of SCM on the value of a firm. Opposed to existing models that limit the observation to chosen facets of SCM or selected value drivers, this holistic approach is adequate to • reflect configurational and operational aspects of SCM, • cover all phases of the product life cycle, • financially compare value impacts of profitability-related and asset-related value drivers, and • assess influences of dynamics and uncertainties on company value.

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    • Brandenburg, Marcus

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  • 2013
  • Book
  • • Marcus Brandenburg
  • • Company value
    • Discounted cash flow
    • Industrial case examples
    • Model-based quantitative research
    • Supply chain management

• A Semantics for Weakly Encapsulated Search in Functional Logic Programs

  Christiansen, J. ., Hanus, M. ., Reck, F. ., & Seidel, D. . (2013). A Semantics for Weakly Encapsulated Search in Functional Logic Programs. In Proceedings of the 15th Symposium on Principles and Practice of Declarative Programming - PPDP 13 (S. 49–60). ACM Press. http://doi.org/10.1145/2505879.2505896

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  Encapsulated search is a key feature of (functional) logic languages. It allows the programmer to access and process different results of a non-deterministic computation within a program. Unfortunately, due to advanced operational features (lazy evaluation, partial values, infinite structures), there is no straightforward definition of the semantics of encapsulated search in functional logic languages. As a consequence, various proposals and implementations are available but a rigorous definition covering all semantical aspects does not exist. In this paper, we analyze the requirements of encapsulated search in a functional logic language like Curry and provide a comprehensive definition that covers weak encapsulation, a modular form of encapsulation, as well as nested applications of search operators. We set up a denotational semantics that distinguishes non-termination and different levels of failures in a computation. The semantics is also the basis of a practical implementation of search operators in the functional logic language Curry.

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    • Christiansen, Jan

  • Fachbereich

    • Fachbereich 3: Information und Kommunikation

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  • 2013
  • Conference Paper
  • • Jan Christiansen
    • Michael Hanus
    • Fabian Reck
    • Daniel Seidel